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Hardy-Weinberg Practice
The following problems were taken
from http://www.biocore.uwo.ca/b22_23/files/Dan/EE/hw_probs.htm. The answers are in
parentheses in each problem.
- In a
class of 50 students, 18 students were non-tasters (the detected no flavor
in the PTC paper) and 32 were tasters. Tasting is dominant (T) and
non-tasting is recessive (t). Assume that the population is in
Hardy-Weinberg equilibrium. What is
the frequency of the homozygous recessive individuals? (36%) Frequency of homozygous dominant individuals? (16%) Frequency of heterozygous individuals? (48%)
- The
frequency of two alleles in a gene pool is 0.1 (A) and 0.9 (a). What is
the percentage in the population of heterozygous individuals? (18%). Of
homozygous recessives? (81%). Assume the population is in Hardy-Weinberg
equilibrium.
- Allele
B for white wool, is dominant over allele b, for
black wool. In a sample of 900 sheep, 891 are white and 9 are black.
Estimate the allelic frequencies in this sample, assuming the population
is in equilibrium. (p=0.9; q=0.1)
- In a
population that is in Hardy-Weinberg equilibrium, the frequency of the
recessive homozygous genotype of a certain trait is 0.09. What is the
percentage of individuals homozygous for the dominant allele? (49%)
- In a
population that is in Hardy-Weinberg equilibrium, 36 percent of the
individuals are recessive homozygotes for a
certain trait. For the same trait, what is the percentage in this
population of homozygous dominant individuals? (16%). Of heterozygous
individuals? (48%)
- Allele
T, for the ability to taste a particular chemical, is dominant over allele
t, for the inability to taste it. At Cornell University, out of 400 surveyed
students, 64 were found to be non tasters. What is the percentage of
heterozygous students? (48%). Assume the population is in equilibrium.
- In
humans, Rh-positive individuals have Rh antigen
on their red blood cells, while Rh-negative individuals do not. Assume
that the Rh-positive phenotype is produced by a dominant allele Rh, and the Rh-negative phenotype is produced by its
recessive allele rh. In a population that is in
Hardy-Weinberg equilibrium, if 84 percent of the individuals are
Rh-positive, what are the frequencies of the Rh
allele and the rh allele at this locus?(p=0.6;
q=0.4)
- In
corn, yellow kernel color is governed by a dominant allele; white, by its
recessive allele. A random sample of 1,000 kernels from a population that
is in equilibrium reveals that 910 are yellow and 90 are white. What are
the frequencies of the yellow and white alleles in this population?
(p=0.7; q=0.3). What is the percentage of heterozygous in this population?
(42%)
- A rare
disease due to a recessive allele which is lethal when homozygous occurs
with a frequency of one in a million. How many individuals in a town of
14,000 can be expected to carry this allele? (28 people)